Rapid desensitization for chlorambucil drug fever
نویسندگان
چکیده
منابع مشابه
Rapid desensitization for chlorambucil drug fever.
Chlorambucil is an oral alkylating agent, introduced in 1953, that is still used as a primary treatment for chronic lymphocytic leukemia (CLL). Chlorambucil is usually well tolerated and often administered intermittently, with intervals of months or years between recurrent courses of treatment. Chlorambucil-induced drug fever presents as fever, rigors, and malaise within hours to days of starti...
متن کاملDesensitization for drug allergy.
PURPOSE OF REVIEW Desensitization for drug allergy is the induction of temporary clinical unresponsiveness to drug antigens. Gradual reintroduction of small doses of drug antigen at fixed time intervals allows for the delivery of full therapeutic doses, protecting patients from anaphylaxis. Rapid desensitizations permit the use of essential antibiotics in severely infected allergic patients or ...
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Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...
متن کاملRapid desensitization for hypersensitivity reactions to medications.
Drug desensitization is the induction of temporary clinical unresponsiveness to drug antigens to which patients have presented severe hypersensitivity reactions. It is typically achieved by gradual reintroduction of small doses of drug antigens at fixed time intervals, and it is aimed at providing increased safety and protection from side effects, including anaphylaxis. Delivery of full therape...
متن کاملRapid desensitization for hypersensitivity reactions to chemotherapeutic drugs; a case series
Usage of cancer chemotherapeutics drugs can be associated with adverse drug reactions. When IgE-mediated drug reactions are formed following administration of a chemotherapeutic drug that is a drug of choice, drug desensitization protocols can be helpful. Hypersensitivity reactions can be allergic or nonallergic, but the clinical manifestations are similar. Rapid drug desensitization (RDD) is e...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2007
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.11604